India Introduces World’s First Genome-Edited Rice Varieties

India has become the first country in the world to unveil genome-edited rice varieties- DRR Dhan 100 (Kamala) and Pusa DST Rice 1- that deliver 25–30% higher yields without introducing foreign DNA. These non-GMO crops are aimed at boosting productivity, reducing emissions, saving water, and transforming Indian agriculture.

Key Highlights

  • Developed by:
    • DRR Dhan 100 (Kamala): Indian Institute of Rice Research, Hyderabad
    • Pusa DST Rice 1: Indian Agricultural Research Institute, Delhi
  • Commercial cultivation timeline: 4–5 years
  • Global significance:
    • World’s first genome-edited rice varieties
    • Expected to replace widely grown varieties like Samba Mahsuri and Cottondora Sannalu (grown over 9 million hectares in India)
  • Target states: Andhra Pradesh, Telangana, Karnataka, Tamil Nadu, Kerala, Puducherry, Bihar, Chhattisgarh, Maharashtra, Madhya Pradesh, Odisha, Jharkhand, and West Bengal

Scientific & Technical Details

  • Technology used:
    • CRISPR-Cas9 system
    • SDN-1 technology (site-directed nuclease-1)- makes precise edits in native DNA without adding foreign genes
  • Regulatory status:
    • Exempt from approval by the Genetic Engineering Appraisal Committee (GEAC) under India’s relaxed rules (SDN-1, SDN-2 exempted since 2022)
    • Approved by: Institutional Biosafety Committees (IBC) and Review Committee on Genetic Manipulation (clearance on 31 May 2023)
  • Performance in Trials:
    • Tested under All India Coordinated Research Project on Rice (kharif 2023 & 2024)
    • Showed strong yield performance under stress conditions
    • Drought and disease tolerance

Agronomic Benefits

  • Yield gains:
    • DRR Dhan 100: 5.37 tonnes/ha vs. 4.5 tonnes/ha of parent Samba Mahsuri; High potential yield (~9 tonnes/hectare); Maturity: in 130 days (15–20 days earlier);
    • Pusa DST Rice 1: ~3.5 tonnes/ha more than parent variety
  • Environmental gains (in ~5 million hectares):
    • Additional paddy production: 4.5 million tonnes
    • Greenhouse gas emissions cut by 20% (32,000 tonnes)
    • Water savings: 7,500 million cubic metres (usable for other crops)
  • Grain quality: No compromise reported

Strategic Vision

  • “Minus 5 and Plus 10” formula: Reduce rice area by 5 million hectares and increase production by 10 million tonnes to free land for pulses and oilseeds
  • Pipeline crops: Genome-edited banana, wheat, tomato, tur, cotton under development in India
  • Budget support: ₹500 crore (Budget 2023–24) allocated for genome editing in agriculture research across ~40 crops

Background & Policy Context

  • Rice in India:
    • Area: ~46 million hectares (kharif + rabi)
    • 2023–24 output: 137 million tonnes
    • 2nd largest rice producer
    • Leading exporter since 2012; ~$12 billion rice exports in FY25
  • Legal framework:
    • In 2022, govt exempted SDN-1 & SDN-2 genome edits from Rules 7–11 of the Environment Protection Act
    • Supreme Court has directed the government to create a national policy on genetically modified crops, which is under consultation
  • ICAR’s Role:
    • Started genome editing in 2018
    • Cleared by Institutional Biosafety Committee & Review Committee on Genetic Manipulation (May 2023)
  • Global context:
    • ~30 countries classify genome-edited crops as non-GMO
    • US and China are leaders in genome-edited crops like rice, maize, soybean, canola, tomato

Criticism & Concerns

  • Scientific concerns: Potential unintended DNA changes (large insertions, deletions, rearrangements)
  • Regulatory concerns: Released without safety testing under India’s relaxed rules;
  • IPR issues: Gene editing tools are proprietary, raising intellectual property rights (IPR) and seed sovereignty concerns
  • ECJ 2018 ruling: European Court of Justice (ECJ) classifies genome-edited crops under GMO rules; India’s deregulation of SDN-1, SDN-2 seen as risky by critics
  • Trade risks: Potential impact on rice export markets if buyers reject gene-edited products; Possible impact on India’s rice export reputation

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